A Prevention-First Approach to MRSA That Cut Infections in Half and Saved $1 Million

Sentara Health reduced hospital-onset MRSA cases by nearly 50% after pairing an automated MRSA risk score in Epic with targeted decolonization workflows. It has avoided an estimated $1.18 million in infection-related costs to date and is on track to reach more than $2 million in savings over five years. How They Did It Automatically calculated […]
By admin
Aug 13, 2026, 3:17 PM

Sentara Health reduced hospital-onset MRSA cases by nearly 50% after pairing an automated MRSA risk score in Epic with targeted decolonization workflows. It has avoided an estimated $1.18 million in infection-related costs to date and is on track to reach more than $2 million in savings over five years.

How They Did It
  • Automatically calculated patients’ MRSA risk based on admission sources and history
  • Allowed nurses to place MRSA prophylaxis orders for high-risk patients at admission
  • Reviewed real-time decolonization compliance reports in daily infection huddles

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